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编辑者： Svitlana Velhush
28年2026月，九州大学的研究团队展示了一种新型水溶性且完全无金属的分子。它能够同时提供荧光成像并作为MRI造影剂。
科学家们对发光有机自由基tris(2,4,6-trichlorophenyl) methyl（TTM）进行了修饰，使其具有水溶性。在水性环境中，该分子在荧光时发出深红色光。
在MRI体模测试中，这种新型造影剂将图像对比度提高了2,5–4,5倍，相比此前已知的水溶性TTM自由基。这为更安全、多功能的诊断工具开辟了道路。
无金属成分降低了传统含钆造影剂所特有的毒性风险。该分子在单一结构中结合了光学和磁共振特性。
研究结果发表在Advanced Science杂志上。该研究得到了Japan Society for the Promotion of Science、Japan Science and Technology Agency及其他基金会的支持。
这一发现将如何影响未来几年的日常临床实践？
科学家们仍在继续优化，但现在已经清楚：这种造影剂可以简化联合研究，其中荧光有助于实时观察，而MRI则有助于组织的深层成像。
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