The Trump administration has announced the allocation of over $5 billion to expand the Genesis Mission, a national program for using artificial intelligence in scientific research, aiming to double the productivity of American science within a decade.
The announcement was made on July 22, 2026, by Michael Kratsios, Assistant to the President and Director of the White House Office of Science and Technology Policy. The initiative encompasses over 15 federal agencies that provide grants, scientific data, and infrastructure. This includes the Departments of Health, Energy, and Homeland Security, as well as NASA and the National Science Foundation.
The Genesis Mission was officially launched by President Trump's executive order on November 24, 2025, as a national mobilization comparable in scale to the Manhattan Project. Initially developed within the Department of Energy, the program quickly grew into a nationwide initiative. Its foundation is the American Science and Security Platform, which includes a cloud infrastructure (American Science Cloud) built and managed by the Department of Energy in collaboration with 17 national laboratories.
"America's greatest scientific achievements have been born from national mobilizations and the creation of new institutions. The Genesis Mission is the next chapter in this tradition," said Kratsios, emphasizing the program's ambition amid global competition with China in artificial intelligence and advanced technologies.
In the first phase, 278 projects were selected from over 5,000 submissions — the highest response rate ever recorded by the Department of Energy for any funding competition. The projects are led by 87 national laboratories, 168 universities, 19 companies, and 4 non-profit organizations. In total, 342 institutions from all 50 states are participating, including 157 private sector companies.
The selected projects address critical challenges, ranging from identifying the root causes of chronic diseases to creating automated laboratories, developing new materials, and analyzing over 150 petabytes of NASA space data. Avatars will be developed to search for treatments for pediatric cancer, accelerate drug discovery, improve nuclear energy and critical minerals, advance intelligent chip design, and promote commercial nuclear energy and quantum technologies.
In the current phase (Phase I), the Department of Energy is allocating $250 million from the total pool of $5 billion. Successful teams will gain access to the Genesis Mission platform, which includes AI agent tools, advanced AI models, specialized software from industrial partners, and supercomputers at national laboratories.
The Genesis Mission is positioned as a turning point in how scientific research is conducted — moving from isolated projects to an integrated system where data, computing power, and AI tools work in sync. This creates an unprecedented opportunity for thousands of researchers nationwide to accelerate the path from hypothesis to discovery and practical application. According to the administration, the program will be a step toward restoring American leadership in science and technology, ensuring national security and energy independence.
