Richard Branson has warned that Donald Trump's policies risk "doing so much damage" to the world.
He added that he does not believe that most Americans support the U.S. president's actions since returning to the White House.
Branson's Virgin Group includes Virgin Atlantic, Virgin Voyages, and Virgin Hotels.
Branson, estimated to be worth $2.8 billion, stated that Trump's economic policies have been "erratic and unpredictable."
Earlier this month, the Trump administration announced tariffs on many of America's trading partners.
The U.S. President then announced a 90-day pause on some measures after a market sell-off.
Trump has repeatedly threatened punitive measures on trading partners, sometimes pausing or reversing them.
Branson said companies and governments would "manage as we always do."
He added, "I honestly think this is a fairly small elite of people around Trump."
Branson spoke at an event marking Virgin Atlantic's new route from London to Riyadh.
About 60% of Virgin Atlantic's capacity goes to the U.S., exposing the carrier to Trump's tariffs.
Virgin Atlantic warned of a slowdown in travel demand from the U.S. to the U.K. in March.
Delta Air Lines reported flat revenue, with the CEO stating they were "acting as if we're going into a recession."
Travelers are showing caution due to concerns that Trump's tariffs will raise prices and curtail economic growth.
In early April, Branson said the Trump administration should "own up to a colossal mistake and change course."
Branson posted on X that U.S. consumer prices will rise as the dollar weakens.