Scientists have created a genetic "toggle switch" for plants, allowing them to control specific traits like fruit ripening and drought resistance. This breakthrough could revolutionize agriculture and help address global challenges.
Researchers at Colorado State University have successfully implemented a synthetic genetic toggle switch in fully grown plants. Synthetic biology involves designing and constructing new DNA segments to function like circuits in electronics. This innovative tool enables scientists to activate or deactivate specific genes within a plant, much like a switch controls a lightbulb.
The research, published in ACS Synthetic Biology, was led by Professor June Medford from the Department of Biology and Professor Ashok Prasad from the Department of Chemical and Biological Engineering. The team focused on overcoming the complexities of multicellular plants, which present a significant challenge compared to single-celled organisms.
The team synthesized plant DNA components and designed a genetic toggle system using mathematical modeling. This approach allowed them to test various combinations before identifying an effective one. They then transformed plants with the selected DNA sequences and observed the results over 12 days.
Professor Medford emphasized the collaborative nature of the project, combining biological expertise with mathematical modeling to identify key signals. The research demonstrates that these circuits function throughout the plant, regulating various functions across its life cycle. Professor Prasad highlighted the potential for farmers to control their crops by activating traits like drought tolerance.
This technology offers numerous benefits to society, including enhanced food security and the development of new materials. It could enable farmers to adapt to unpredictable climates and improve crop yields. The ability to control plant traits opens up exciting possibilities for agriculture and environmental sustainability.