NAD+ infusions and supplements are increasingly popular in 2025 as potential longevity and wellness enhancers [1, 3]. NAD+, or nicotinamide adenine dinucleotide, is a vital coenzyme present in every cell, playing a crucial role in energy production, DNA repair, and overall cellular function [1, 4, 12]. As we age, NAD+ levels decline, impacting our health and vitality [1, 3].
The Science Behind NAD+
NAD+ is essential for various cellular processes, including energy metabolism, DNA repair, and immune support [1, 4, 12]. It helps convert nutrients into energy and protects cells from damage [1, 4]. Maintaining healthy NAD+ levels is crucial for overall well-being and healthy aging [3, 4].
NAD+ Infusions: A Direct Boost
NAD+ IV therapy involves administering NAD+ directly into the bloodstream, ensuring 100% bioavailability [1]. This method bypasses the digestive system, allowing for faster and more efficient absorption compared to oral supplements [1]. Some clinics offer customized doses, administered by licensed professionals [21].
NAD+ Supplements: Boosting from Within
NAD+ supplements typically contain precursors like nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), which the body converts into NAD+ [3, 5]. These supplements aim to support natural NAD+ production and improve cellular function [3]. Niagen Bioscience, formerly ChromaDex, is a key player in NAD+ research and produces the patented Niagen, a form of NR [6, 8, 9].
Lifestyle Changes: A Natural Approach
Besides infusions and supplements, lifestyle changes can also boost NAD+ levels [2, 13]. Regular exercise, a healthy diet rich in vitamin B3, sufficient rest, and stress management can naturally increase NAD+ [2, 13].